CSMS 66347264·Operational·September 25, 2025·View on csms.cbp.gov ↗

U.S. Food and Drug Administration (FDA) Supplemental Guide DRAFT Version 2.6 is Now Available

Plain-English explanation

CSMS 66347264 is a U.S. Customs and Border Protection (CBP) Cargo Systems Messaging Service bulletin (operational), published on September 25, 2025. It carries the official CBP guidance brokers and importers must follow for the topic — "U.S. Food and Drug Administration (FDA) Supplemental Guide DRAFT Version 2.6 is Now Available". CSMS messages are the operational layer between Commerce determinations and at-the-border collections: when Commerce publishes a new rate, scope ruling, or instruction, CBP turns it into a CSMS that ACE/ACS systems and brokers act on.

Message body

Full text as published by U.S. Customs and Border Protection

CSMS # 66347264 - U.S. Food and Drug Administration (FDA) Supplemental Guide DRAFT Version 2.6 is Now Available U.S. Customs and Border Protection sent this bulletin at 09/25/2025 04:24 PM EDT Cargo Systems Messaging Service CSMS # 66347264 - U.S. Food and Drug Administration (FDA) Supplemental Guide DRAFT Version 2.6 is Now Available The U.S. Food and Drug Administration (FDA) Supplemental Guide (SG) draft version 2.6 has been posted in the ‘Draft Chapters: Future Capabilities’ section of CBP.gov. Review the change log in the document for the specific changes. To support the import community’s request for a transition period where possible, the severity (warning or reject) of the validations associated with these changes in the tobacco message set, and their respective deployment dates will vary as indicated in the attachment. In addition to the revisions in the attachment, the following editorial changes are included in SG version 2.6 for clarification purposes: Align import scenario for Intended Use Code (IUC) 100.000 and 210.000 (personal importation) for all commodities Update PG01 notes in several commodities to clarify when IUC is mandatory, conditional or optional In the tobacco section, PG02, indicate product code information for consumer use and electronic nicotine delivery systems (ENDS) products Appendix B: update description for Food Facility Registration Exemption (FME) code B. For questions about the changes to SG 2.6 contact FDA ACE Support: ACE_Support@fda.hhs.gov . FDA ACE Supplemental Guide version two point six Business Rule Revisions.pdf Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page . You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact subscriberhelp.govdelivery.com . This service is provided to you at no charge by U.S. Customs and Border Protection . Privacy Policy | GovDelivery is providing this information on behalf of U.S. Department of Homeland Security, and may not use the information for any other purposes. Powered by Privacy Policy | Cookie Statement | Help

Frequently asked questions

What is CSMS 66347264?

CSMS 66347264 is a U.S. Customs and Border Protection (CBP) Cargo Systems Messaging Service bulletin titled "U.S. Food and Drug Administration (FDA) Supplemental Guide DRAFT Version 2.6 is Now Available". CSMS bulletins are the operational instructions CBP issues to brokers, importers, and ACE filers covering rate changes, system updates, scope guidance, and other day-to-day customs-operations changes.

When was CSMS 66347264 published?

CBP published CSMS 66347264 on September 25, 2025. The bulletin's instructions are typically operative as of the publication date unless the body specifies a different effective date.

Is the CBP CSMS the legally binding instruction?

Yes — for at-the-border filing and entry collection. CSMS messages translate Commerce's Federal Register determinations into operational CBP instructions that ACE/ACS systems and brokers execute. The Federal Register notice is the underlying legal authority; the CSMS is the operational implementation. Both should be read together when reconciling a rate or scope change.

Learn more

Tandom guides relevant to CBP CSMS messages

Subscribe to and triage CBP CSMS messages

How to subscribe to CBP Cargo Systems Messaging Service and triage the messages that change broker filing behavior, without losing the ones that matter.

Open resource

Real-time alerts when a CSMS message changes a duty rate

Set up alerts when a CBP CSMS message changes a duty rate on an HTS code you depend on. Built for brokers, forwarders, and importer compliance teams.