CSMS 66342113·Operational·September 25, 2025·View on csms.cbp.gov ↗

U.S. Food and Drug Administration (FDA) Supplemental Guide Version 2.5.13 is Now Available

Plain-English explanation

CSMS 66342113 is a U.S. Customs and Border Protection (CBP) Cargo Systems Messaging Service bulletin (operational), published on September 25, 2025. It carries the official CBP guidance brokers and importers must follow for the topic — "U.S. Food and Drug Administration (FDA) Supplemental Guide Version 2.5.13 is Now Available". CSMS messages are the operational layer between Commerce determinations and at-the-border collections: when Commerce publishes a new rate, scope ruling, or instruction, CBP turns it into a CSMS that ACE/ACS systems and brokers act on.

Message body

Full text as published by U.S. Customs and Border Protection

CSMS # 66342113 - U.S. Food and Drug Administration (FDA) Supplemental Guide Version 2.5.13 is Now Available U.S. Customs and Border Protection sent this bulletin at 09/25/2025 10:01 AM EDT Cargo Systems Messaging Service CSMS # 66342113 - U.S. Food and Drug Administration (FDA) Supplemental Guide Version 2.5.13 is Now Available U.S. Food and Drug Administration (FDA) Supplemental Guide (SG), version 2.5.13, has been posted on CBP.gov and can be found here: https://www.cbp.gov/document/guidance/fda-supplemental-guide The change associated with this version has been deployed in certification and production. This version makes Intended Use Code (IUC) 920.000 a valid code for program code TOB. For questions contact FDA ACE Support ACE_Support@fda.hhs.gov . Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page . You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact subscriberhelp.govdelivery.com . This service is provided to you at no charge by U.S. Customs and Border Protection . Privacy Policy | GovDelivery is providing this information on behalf of U.S. Department of Homeland Security, and may not use the information for any other purposes. Powered by Privacy Policy | Cookie Statement | Help

Frequently asked questions

What is CSMS 66342113?

CSMS 66342113 is a U.S. Customs and Border Protection (CBP) Cargo Systems Messaging Service bulletin titled "U.S. Food and Drug Administration (FDA) Supplemental Guide Version 2.5.13 is Now Available". CSMS bulletins are the operational instructions CBP issues to brokers, importers, and ACE filers covering rate changes, system updates, scope guidance, and other day-to-day customs-operations changes.

When was CSMS 66342113 published?

CBP published CSMS 66342113 on September 25, 2025. The bulletin's instructions are typically operative as of the publication date unless the body specifies a different effective date.

Is the CBP CSMS the legally binding instruction?

Yes — for at-the-border filing and entry collection. CSMS messages translate Commerce's Federal Register determinations into operational CBP instructions that ACE/ACS systems and brokers execute. The Federal Register notice is the underlying legal authority; the CSMS is the operational implementation. Both should be read together when reconciling a rate or scope change.

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