CSMS 64545745·System update·March 26, 2025·View on csms.cbp.gov ↗

REMINDER: Upcoming deployment for U.S. Food and Drug Administration (FDA) ACE changes specified in FDA ACE Supplemental Guide 2.5.12

Plain-English explanation

CSMS 64545745 is a U.S. Customs and Border Protection (CBP) Cargo Systems Messaging Service bulletin (system update), published on March 26, 2025. It carries the official CBP guidance brokers and importers must follow for the topic — "REMINDER: Upcoming deployment for U.S. Food and Drug Administration (FDA) ACE changes specified in FDA ACE Supplemental Guide 2.5.12". CSMS messages are the operational layer between Commerce determinations and at-the-border collections: when Commerce publishes a new rate, scope ruling, or instruction, CBP turns it into a CSMS that ACE/ACS systems and brokers act on.

Message body

Full text as published by U.S. Customs and Border Protection

CSMS # 64545745 - REMINDER: Upcoming deployment for U.S. Food and Drug Administration (FDA) ACE changes specified in FDA ACE Supplemental Guide 2.5.12 U.S. Customs and Border Protection sent this bulletin at 03/26/2025 04:32 PM EDT Cargo Systems Messaging Service CSMS # 64545745 - REMINDER: Upcoming deployment for U.S. Food and Drug Administration (FDA) ACE changes specified in FDA ACE Supplemental Guide 2.5.12 The changes related to the U.S. Food and Drug Administration (FDA) ACE Supplemental Guide (Draft Version 2.5.12 updated January 15, 2025) that are currently in Customs and Border Protection (CBP’s) CERTIFICATION environment will be deployed to CBP PRODUCTION environment on March 29, 2025. For questions, contact FDA ACE Support ACE_Support@fda.hhs.gov . Related messages: CSMS # 63839331, 64063659, 64232214, 64404180 Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page . You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact subscriberhelp.govdelivery.com . This service is provided to you at no charge by U.S. Customs and Border Protection . Privacy Policy | GovDelivery is providing this information on behalf of U.S. Department of Homeland Security, and may not use the information for any other purposes. Powered by Privacy Policy | Cookie Statement | Help

Frequently asked questions

What is CSMS 64545745?

CSMS 64545745 is a U.S. Customs and Border Protection (CBP) Cargo Systems Messaging Service bulletin titled "REMINDER: Upcoming deployment for U.S. Food and Drug Administration (FDA) ACE changes specified in FDA ACE Supplemental Guide 2.5.12". CSMS bulletins are the operational instructions CBP issues to brokers, importers, and ACE filers covering rate changes, system updates, scope guidance, and other day-to-day customs-operations changes.

When was CSMS 64545745 published?

CBP published CSMS 64545745 on March 26, 2025. The bulletin's instructions are typically operative as of the publication date unless the body specifies a different effective date.

Is the CBP CSMS the legally binding instruction?

Yes — for at-the-border filing and entry collection. CSMS messages translate Commerce's Federal Register determinations into operational CBP instructions that ACE/ACS systems and brokers execute. The Federal Register notice is the underlying legal authority; the CSMS is the operational implementation. Both should be read together when reconciling a rate or scope change.

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