CSMS 64404180·System update·March 13, 2025·View on csms.cbp.gov ↗

Deployment Reminder (and CERT Update) for Changes Related to FDA ACE Supplemental Guide 2.5.12

Plain-English explanation

CSMS 64404180 is a U.S. Customs and Border Protection (CBP) Cargo Systems Messaging Service bulletin (system update), published on March 13, 2025. It carries the official CBP guidance brokers and importers must follow for the topic — "Deployment Reminder (and CERT Update) for Changes Related to FDA ACE Supplemental Guide 2.5.12". CSMS messages are the operational layer between Commerce determinations and at-the-border collections: when Commerce publishes a new rate, scope ruling, or instruction, CBP turns it into a CSMS that ACE/ACS systems and brokers act on.

Message body

Full text as published by U.S. Customs and Border Protection

CSMS # 64404180 - Deployment Reminder (and CERT Update) for Changes Related to FDA ACE Supplemental Guide 2.5.12 U.S. Customs and Border Protection sent this bulletin at 03/13/2025 09:55 AM EDT Cargo Systems Messaging Service CSMS # 64404180 - Deployment Reminder (and CERT Update) for Changes Related to FDA ACE Supplemental Guide 2.5.12 The changes related to the U.S. Food and Drug Administration (FDA) ACE Supplemental Guide (Draft Version 2.5.12 updated January 15, 2025) that are expected to deploy on March 29, 2025, to Customs and Border Protection (CBP’s) PRODUCTION environment, are now available in CBP’s CERTIFICATION environment. Please refer to CSMS # 63839331 for the specific details. For questions, contact FDA ACE Support ACE_Support@fda.hhs.gov . Related messages: CSMS # 63839331 , 64063659, 64232214 Update your subscriptions, modify your password or e-mail address, or stop subscriptions at any time on your Subscriber Preferences Page . You will need to use your e-mail address to log in. If you have questions or problems with the subscription service, please contact subscriberhelp.govdelivery.com . This service is provided to you at no charge by U.S. Customs and Border Protection . Privacy Policy | GovDelivery is providing this information on behalf of U.S. Department of Homeland Security, and may not use the information for any other purposes. Powered by Privacy Policy | Cookie Statement | Help

Frequently asked questions

What is CSMS 64404180?

CSMS 64404180 is a U.S. Customs and Border Protection (CBP) Cargo Systems Messaging Service bulletin titled "Deployment Reminder (and CERT Update) for Changes Related to FDA ACE Supplemental Guide 2.5.12". CSMS bulletins are the operational instructions CBP issues to brokers, importers, and ACE filers covering rate changes, system updates, scope guidance, and other day-to-day customs-operations changes.

When was CSMS 64404180 published?

CBP published CSMS 64404180 on March 13, 2025. The bulletin's instructions are typically operative as of the publication date unless the body specifies a different effective date.

Is the CBP CSMS the legally binding instruction?

Yes — for at-the-border filing and entry collection. CSMS messages translate Commerce's Federal Register determinations into operational CBP instructions that ACE/ACS systems and brokers execute. The Federal Register notice is the underlying legal authority; the CSMS is the operational implementation. Both should be read together when reconciling a rate or scope change.

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